Endocrine Abstracts

Background: Glucose-dependent insulinotropic polypeptide (GIP) is a gastrointestinal hormone that is secreted in response to food intake. GIP acts on various tissues, including pancreatic ß-cells, via interaction with its G-protein-coupled receptor. Some studies in rodents suggested that GIP directly links overnutrition to obesity. GIP exerts a physiological role on lipid uptake into adipocytes.Objectives: To analyse the effect of GIP-Infusions on c...